Nucleolin-aptamer therapy in retinoblastoma: molecular changes and mass spectrometry–based imaging

Retinoblastoma (RB) is an intraocular childhood tumor which, if left untreated, leads to blindness and mortality. Nucleolin (NCL) protein which is differentially expressed on the tumor cell surface, binds ligands and regulates carcinogenesis and angiogenesis. We found that NCL is over expressed in R...

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發表在:Mol Ther Nucleic Acids
Main Authors: Subramanian, Nithya, Srimany, Amitava, Kanwar, Jagat R, Kanwar, Rupinder K, Akilandeswari, Balachandran, Rishi, Pukhraj, Khetan, Vikas, Vasudevan, Madavan, Pradeep, Thalappil, Krishnakumar, Subramanian
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2016
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Original Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5023409/
https://ncbi.nlm.nih.gov/pubmed/27574784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2016.70
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