Nucleolin-aptamer therapy in retinoblastoma: molecular changes and mass spectrometry–based imaging

Retinoblastoma (RB) is an intraocular childhood tumor which, if left untreated, leads to blindness and mortality. Nucleolin (NCL) protein which is differentially expressed on the tumor cell surface, binds ligands and regulates carcinogenesis and angiogenesis. We found that NCL is over expressed in R...

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Dades bibliogràfiques
Publicat a:Mol Ther Nucleic Acids
Autors principals: Subramanian, Nithya, Srimany, Amitava, Kanwar, Jagat R, Kanwar, Rupinder K, Akilandeswari, Balachandran, Rishi, Pukhraj, Khetan, Vikas, Vasudevan, Madavan, Pradeep, Thalappil, Krishnakumar, Subramanian
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5023409/
https://ncbi.nlm.nih.gov/pubmed/27574784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2016.70
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