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EpCAM Aptamer-siRNA Chimera Targets and Regress Epithelial Cancer
Epithelial cell adhesion molecule (EpCAM), a cancer stem cell (CSC) marker is over expressed in epithelial cancers and in retinoblastoma (RB). We fabricated an EpCAM targeting aptamer-siRNA chimera and investigated its anti-tumor property and EpCAM intracellular domain (EpICD) mediated signaling in...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4503753/ https://ncbi.nlm.nih.gov/pubmed/26176230 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0132407 |
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