Target-specific delivery of doxorubicin to retinoblastoma using epithelial cell adhesion molecule aptamer

PURPOSE: To study target-specific delivery of doxorubicin (Dox) using an RNA aptamer against epithelial cell adhesion molecule (EpCAM) in retinoblastoma (RB) cells. METHODS: The binding affinity of the EpCAM aptamer to RB primary tumor cells, Y79 and WERI-Rb1 cells, and Müller glial cell lines were...

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Bibliografiske detaljer
Main Authors: Subramanian, Nithya, Raghunathan, Vaishnavi, Kanwar, Jagat R., Kanwar, Rupinder K., Elchuri, Sailaja V., Khetan, Vikas, Krishnakumar, Subramanian
Format: Artigo
Sprog:Inglês
Udgivet: Molecular Vision 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3513190/
https://ncbi.nlm.nih.gov/pubmed/23213278
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