Nucleolin-aptamer therapy in retinoblastoma: molecular changes and mass spectrometry–based imaging

Retinoblastoma (RB) is an intraocular childhood tumor which, if left untreated, leads to blindness and mortality. Nucleolin (NCL) protein which is differentially expressed on the tumor cell surface, binds ligands and regulates carcinogenesis and angiogenesis. We found that NCL is over expressed in R...

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Detalhes bibliográficos
Publicado no:Mol Ther Nucleic Acids
Main Authors: Subramanian, Nithya, Srimany, Amitava, Kanwar, Jagat R, Kanwar, Rupinder K, Akilandeswari, Balachandran, Rishi, Pukhraj, Khetan, Vikas, Vasudevan, Madavan, Pradeep, Thalappil, Krishnakumar, Subramanian
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5023409/
https://ncbi.nlm.nih.gov/pubmed/27574784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2016.70
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