A Tetraspecific VHH-Based Neutralizing Antibody Modifies Disease Outcome in Three Animal Models of Clostridium difficile Infection

Clostridium difficile infection (CDI), a leading cause of nosocomial infection, is a serious disease in North America, Europe, and Asia. CDI varies greatly from asymptomatic carriage to life-threatening diarrhea, toxic megacolon, and toxemia. The incidence of community-acquired infection has increas...

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Detaylı Bibliyografya
Yayımlandı:Clin Vaccine Immunol
Asıl Yazarlar: Schmidt, Diane J., Beamer, Gillian, Tremblay, Jacqueline M., Steele, Jennifer A., Kim, Hyeun Bum, Wang, Yaunkai, Debatis, Michele, Sun, Xingmin, Kashentseva, Elena A., Dmitriev, Igor P., Curiel, David T., Shoemaker, Charles B., Tzipori, Saul
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2016
Konular:
Clinical Immunology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5014919/
https://ncbi.nlm.nih.gov/pubmed/27413067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00730-15
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