Adenovirus Vector Expressing Stx1/Stx2-Neutralizing Agent Protects Piglets Infected with Escherichia coli O157:H7 against Fatal Systemic Intoxication

Hemolytic-uremic syndrome (HUS), caused by Shiga toxin (Stx)-producing Escherichia coli (STEC), remains untreatable. Production of human monoclonal antibodies against Stx, which are highly effective in preventing Stx sequelae in animal models, is languishing due to cost and logistics. We reported pr...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Sheoran, Abhineet S., Dmitriev, Igor P., Kashentseva, Elena A., Cohen, Ocean, Mukherjee, Jean, Debatis, Michelle, Shearer, Jonathan, Tremblay, Jacqueline M., Beamer, Gillian, Curiel, David T., Shoemaker, Charles B., Tzipori, Saul
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Bacterial Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4288880/
https://ncbi.nlm.nih.gov/pubmed/25368111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.02360-14
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados