Human Antibody against Shiga Toxin 2 Administered to Piglets after the Onset of Diarrhea Due to Escherichia coli O157:H7 Prevents Fatal Systemic Complications

Infection of children with Shiga toxin (Stx)-producing Escherichia coli (STEC) can lead to hemolytic-uremic syndrome (HUS) in 5 to 10% of patients. Stx2, one of two toxins liberated by the bacterium, is directly linked with HUS. We have previously shown that Stx-specific human monoclonal antibodies...

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Detalhes bibliográficos
Main Authors: Sheoran, Abhineet S., Chapman-Bonofiglio, Susan, Harvey, Barrett R., Mukherjee, Jean, Georgiou, George, Donohue-Rolfe, Arthur, Tzipori, Saul
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1201267/
https://ncbi.nlm.nih.gov/pubmed/16040972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.8.4607-4613.2005
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