Selective Evolution of Ligands by Exponential Enrichment to Identify RNA Aptamers against Shiga Toxins

Infection with Shiga toxin- (Stx-) producing E. coli causes life threatening hemolytic uremic syndrome (HUS), a leading cause of acute renal failure in children. Of the two antigenically distinct toxins, Stx1 and Stx2, Stx2 is more firmly linked with the development of HUS. In the present study, sel...

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Main Authors: Challa, Sreerupa, Tzipori, Saul, Sheoran, Abhineet
格式: Artigo
語言:Inglês
出版: Hindawi Publishing Corporation 2014
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4009280/
https://ncbi.nlm.nih.gov/pubmed/24839553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/214929
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