Selective Evolution of Ligands by Exponential Enrichment to Identify RNA Aptamers against Shiga Toxins

Infection with Shiga toxin- (Stx-) producing E. coli causes life threatening hemolytic uremic syndrome (HUS), a leading cause of acute renal failure in children. Of the two antigenically distinct toxins, Stx1 and Stx2, Stx2 is more firmly linked with the development of HUS. In the present study, sel...

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Hauptverfasser: Challa, Sreerupa, Tzipori, Saul, Sheoran, Abhineet
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4009280/
https://ncbi.nlm.nih.gov/pubmed/24839553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/214929
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