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Evaluation of Fab and F(ab′)(2) Fragments and Isotype Variants of a Recombinant Human Monoclonal Antibody against Shiga Toxin 2

5C12 HuMAb is a human monoclonal antibody against the A subunit of Shiga toxin 2 (Stx2). We have previously shown that 5C12 HuMAb effectively neutralizes the cytotoxic effects of this toxin by redirecting its transport within the cell and also by neutralizing the toxin's ability to inhibit prot...

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Detaylı Bibliyografya
Asıl Yazarlar: Akiyoshi, Donna E., Sheoran, Abhineet S., Rich, Curtis M., Richard, L., Chapman-Bonofiglio, Susan, Tzipori, Saul
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology (ASM) 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825921/
https://ncbi.nlm.nih.gov/pubmed/20086088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00867-09
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