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Evaluation of Fab and F(ab′)(2) Fragments and Isotype Variants of a Recombinant Human Monoclonal Antibody against Shiga Toxin 2
5C12 HuMAb is a human monoclonal antibody against the A subunit of Shiga toxin 2 (Stx2). We have previously shown that 5C12 HuMAb effectively neutralizes the cytotoxic effects of this toxin by redirecting its transport within the cell and also by neutralizing the toxin's ability to inhibit prot...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2825921/ https://ncbi.nlm.nih.gov/pubmed/20086088 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00867-09 |
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