Adenovirus Vector Expressing Stx1/Stx2-Neutralizing Agent Protects Piglets Infected with Escherichia coli O157:H7 against Fatal Systemic Intoxication

Hemolytic-uremic syndrome (HUS), caused by Shiga toxin (Stx)-producing Escherichia coli (STEC), remains untreatable. Production of human monoclonal antibodies against Stx, which are highly effective in preventing Stx sequelae in animal models, is languishing due to cost and logistics. We reported pr...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Infect Immun
Autores principales: Sheoran, Abhineet S., Dmitriev, Igor P., Kashentseva, Elena A., Cohen, Ocean, Mukherjee, Jean, Debatis, Michelle, Shearer, Jonathan, Tremblay, Jacqueline M., Beamer, Gillian, Curiel, David T., Shoemaker, Charles B., Tzipori, Saul
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2014
Materias:
Bacterial Infections
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4288880/
https://ncbi.nlm.nih.gov/pubmed/25368111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.02360-14
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares