Adenovirus Vector Expressing Stx1/Stx2-Neutralizing Agent Protects Piglets Infected with Escherichia coli O157:H7 against Fatal Systemic Intoxication

Hemolytic-uremic syndrome (HUS), caused by Shiga toxin (Stx)-producing Escherichia coli (STEC), remains untreatable. Production of human monoclonal antibodies against Stx, which are highly effective in preventing Stx sequelae in animal models, is languishing due to cost and logistics. We reported pr...

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Detaylı Bibliyografya
Yayımlandı:Infect Immun
Asıl Yazarlar: Sheoran, Abhineet S., Dmitriev, Igor P., Kashentseva, Elena A., Cohen, Ocean, Mukherjee, Jean, Debatis, Michelle, Shearer, Jonathan, Tremblay, Jacqueline M., Beamer, Gillian, Curiel, David T., Shoemaker, Charles B., Tzipori, Saul
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2014
Konular:
Bacterial Infections
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4288880/
https://ncbi.nlm.nih.gov/pubmed/25368111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.02360-14
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