Adenovirus Vector Expressing Stx1/Stx2-Neutralizing Agent Protects Piglets Infected with Escherichia coli O157:H7 against Fatal Systemic Intoxication

Hemolytic-uremic syndrome (HUS), caused by Shiga toxin (Stx)-producing Escherichia coli (STEC), remains untreatable. Production of human monoclonal antibodies against Stx, which are highly effective in preventing Stx sequelae in animal models, is languishing due to cost and logistics. We reported pr...

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Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Infect Immun
Päätekijät: Sheoran, Abhineet S., Dmitriev, Igor P., Kashentseva, Elena A., Cohen, Ocean, Mukherjee, Jean, Debatis, Michelle, Shearer, Jonathan, Tremblay, Jacqueline M., Beamer, Gillian, Curiel, David T., Shoemaker, Charles B., Tzipori, Saul
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2014
Aiheet:
Bacterial Infections
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4288880/
https://ncbi.nlm.nih.gov/pubmed/25368111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.02360-14
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