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MBX-500 Is Effective for Treatment of Clostridium difficile Infection in Gnotobiotic Piglets
The novel antibiotic MBX-500, dosed at 100, 200, or 400 mg/kg twice daily for 7 days, was evaluated for the treatment of Clostridium difficile infection (CDI) in the gnotobiotic pig model. MBX-500 increased survival at all doses and at high doses improved clinical signs and reduced lesion severity,...
में बचाया:
| मुख्य लेखकों: | , , , , , |
|---|---|
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
American Society for Microbiology
2013
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3719748/ https://ncbi.nlm.nih.gov/pubmed/23689716 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00304-13 |
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