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Beneficial Effect of Oral Tigecycline Treatment on Clostridium difficile Infection in Gnotobiotic Piglets

The efficacy of oral tigecycline treatment (2 mg/kg of body weight for 7 days) of Clostridium difficile infection (CDI) was evaluated in the gnotobiotic pig model, and its effect on human gut microflora transplanted into the gnotobiotic pig was determined. Tigecycline oral treatment improved surviva...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Kim, Hyeun Bum, Zhang, Quanshun, Sun, Xingmin, Beamer, Gillian, Wang, Yuankai, Tzipori, Saul
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249528/
https://ncbi.nlm.nih.gov/pubmed/25267665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03447-14
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