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Beneficial Effect of Oral Tigecycline Treatment on Clostridium difficile Infection in Gnotobiotic Piglets

The efficacy of oral tigecycline treatment (2 mg/kg of body weight for 7 days) of Clostridium difficile infection (CDI) was evaluated in the gnotobiotic pig model, and its effect on human gut microflora transplanted into the gnotobiotic pig was determined. Tigecycline oral treatment improved surviva...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Kim, Hyeun Bum, Zhang, Quanshun, Sun, Xingmin, Beamer, Gillian, Wang, Yuankai, Tzipori, Saul
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249528/
https://ncbi.nlm.nih.gov/pubmed/25267665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03447-14
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