Systemically Administered IgG Anti-Toxin Antibodies Protect the Colonic Mucosa during Infection with Clostridium difficile in the Piglet Model

The use of anti-toxin human monoclonal antibodies (HMab) as treatment for C. difficile infection has been investigated in animal models and human clinical trials as an alternative to or in combination with traditional antibiotic therapy. While HMab therapy appears to be a promising option, how syste...

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Bibliografiska uppgifter
Huvudupphovsmän: Cohen, Ocean R., Steele, Jennifer A., Zhang, Quanshun, Schmidt, Diane J., Wang, Yuankai, Hamel, Philip E. S., Beamer, Gillian, Xu, Bingling, Tzipori, Saul
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2014
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4210241/
https://ncbi.nlm.nih.gov/pubmed/25347821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0111075
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