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Bayesian Two-stage Biomarker-based Adaptive Design for Targeted Therapy Development
We propose a Bayesian two-stage biomarker-based adaptive randomization (AR) design for the development of targeted agents. The design has three main goals: (1) to test the treatment efficacy, (2) to identify prognostic and predictive markers for the targeted agents, and (3) to provide better treatme...
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| Vydáno v: | Stat Biosci |
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| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5014437/ https://ncbi.nlm.nih.gov/pubmed/27617040 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12561-014-9124-2 |
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