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Bayesian adaptive randomization designs for targeted agent development

BACKGROUND: With better understanding of the disease’s etiology and mechanism, many targeted agents are being developed to tackle the root cause of problems, hoping to offer more effective and less toxic therapies. Targeted agents, however, do not work for everyone. Hence, the development of target...

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Publicat a:Clin Trials
Autors principals: Lee, J. Jack, Gu, Xuemin, Liu, Suyu
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5110207/
https://ncbi.nlm.nih.gov/pubmed/20571130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1740774510373120
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