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Phase II trial design with Bayesian adaptive randomization and predictive probability
We propose a randomized phase II clinical trial design based on Bayesian adaptive randomization and predictive probability monitoring. Adaptive randomization assigns more patients to a more efficacious treatment arm by comparing the posterior probabilities of efficacy between different arms. We cont...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3832255/ https://ncbi.nlm.nih.gov/pubmed/24259753 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1467-9876.2011.01006.x |
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