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Bayesian adaptive phase II screening design for combination trials

BACKGROUND: Trials of combination therapies for the treatment of cancer are playing an increasingly important role in the battle against this disease. To more efficiently handle the large number of combination therapies that must be tested, we propose a novel Bayesian phase II adaptive screening des...

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Detalhes bibliográficos
Main Authors: Cai, Chunyan, Yuan, Ying, Johnson, Valen E
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3867529/
https://ncbi.nlm.nih.gov/pubmed/23359875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1740774512470316
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