Chargement en cours...
BAYESIAN PHASE I/II ADAPTIVELY RANDOMIZED ONCOLOGY TRIALS WITH COMBINED DRUGS
We propose a new integrated phase I/II trial design to identify the most efficacious dose combination that also satisfies certain safety requirements for drug-combination trials. We first take a Bayesian copula-type model for dose finding in phase I. After identifying a set of admissible doses, we i...
Enregistré dans:
| Auteurs principaux: | , |
|---|---|
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2011
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3286607/ https://ncbi.nlm.nih.gov/pubmed/22375162 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1214/10-AOAS433 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|