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A Bayesian design for phase II clinical trials with delayed responses based on multiple imputation
Interimmonitoring is routinely conducted in phase II clinical trials to terminate the trial early if the experimental treatment is futile. Interim monitoring requires that patients’ responses be ascertained shortly after the initiation of treatment so that the outcomes are known by the time the inte...
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| Publicado no: | Stat Med |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4435968/ https://ncbi.nlm.nih.gov/pubmed/24817556 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.6200 |
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