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Bayesian Adaptive Randomization and Trial Monitoring with Predictive Probability for Time-to-event Endpoint
There has been much development in Bayesian adaptive designs in clinical trials. In the Bayesian paradigm, the posterior predictive distribution characterizes the future possible outcomes given the currently observed data. Based on the interim time-to-event data, we develop a new phase II trial desi...
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| Pubblicato in: | Stat Biosci |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6294453/ https://ncbi.nlm.nih.gov/pubmed/30559900 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12561-017-9199-7 |
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