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Bayesian Adaptive Randomization and Trial Monitoring with Predictive Probability for Time-to-event Endpoint

There has been much development in Bayesian adaptive designs in clinical trials. In the Bayesian paradigm, the posterior predictive distribution characterizes the future possible outcomes given the currently observed data. Based on the interim time-to-event data, we develop a new phase II trial desi...

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Vydáno v:Stat Biosci
Hlavní autoři: Yin, Guosheng, Chen, Nan, Lee, J. Jack
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6294453/
https://ncbi.nlm.nih.gov/pubmed/30559900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12561-017-9199-7
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