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Bayesian Two-step Lasso Strategy for Biomarker Selection in Personalized Medicine Development for Time-to-Event Endpoints

Clinical trial designs for targeted therapy development are progressing toward the goal of personalized medicine. Motivated by the need of ongoing efforts to develop targeted agents for lung cancer patients, we propose a Bayesian two-step Lasso procedure for biomarker selection under the proportiona...

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Detalhes bibliográficos
Main Authors: Gu, Xuemin, Yin, Guosheng, Lee, J. Jack
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3873734/
https://ncbi.nlm.nih.gov/pubmed/24075829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cct.2013.09.009
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