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Milestone prediction for time-to-event endpoint monitoring in clinical trials

Predicting the times of milestone events, ie, interim and final analyses in clinical trials, helps resource planning. This manuscript presents and compares several easily implemented methods for predicting when a milestone event is achieved. We show that it is beneficial to combine the predictions f...

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Publicat a:Pharm Stat
Autors principals: Ou, Fang-Shu, Heller, Martin, Shi, Qian
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6777948/
https://ncbi.nlm.nih.gov/pubmed/30806485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pst.1934
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