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Blinded continuous monitoring in clinical trials with recurrent event endpoints
In studies with recurrent event endpoints, misspecified assumptions of event rates or dispersion can lead to underpowered trials or overexposure of patients. Specification of overdispersion is often a particular problem as it is usually not reported in clinical trial publications. Changing event rat...
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| Publié dans: | Pharm Stat |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
John Wiley and Sons Inc.
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6587844/ https://ncbi.nlm.nih.gov/pubmed/30345693 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pst.1907 |
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