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Blinded continuous monitoring in clinical trials with recurrent event endpoints
In studies with recurrent event endpoints, misspecified assumptions of event rates or dispersion can lead to underpowered trials or overexposure of patients. Specification of overdispersion is often a particular problem as it is usually not reported in clinical trial publications. Changing event rat...
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| Pubblicato in: | Pharm Stat |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley and Sons Inc.
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6587844/ https://ncbi.nlm.nih.gov/pubmed/30345693 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pst.1907 |
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