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A predictive probability design for phase II cancer clinical trials

BACKGROUND: Two- or three-stage designs are commonly used in phase II cancer clinical trials. These designs possess good frequentist properties and allow early termination of the trial when the interim data indicate that the experimental regimen is inefficacious. The rigid study design, however, can...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Clin Trials
Hauptverfasser: Lee, J. Jack, Liu, Diane D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5626665/
https://ncbi.nlm.nih.gov/pubmed/18375647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1740774508089279
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