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A predictive probability design for phase II cancer clinical trials

BACKGROUND: Two- or three-stage designs are commonly used in phase II cancer clinical trials. These designs possess good frequentist properties and allow early termination of the trial when the interim data indicate that the experimental regimen is inefficacious. The rigid study design, however, can...

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Bibliographic Details
Published in:Clin Trials
Main Authors: Lee, J. Jack, Liu, Diane D.
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5626665/
https://ncbi.nlm.nih.gov/pubmed/18375647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1740774508089279
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