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Rational Clinical Experiment: Assessing Prior Probability and Its Impact on the Success of Phase II Clinical Trials

PURPOSE: Despite a robust clinical trial enterprise and encouraging phase II results, the vast minority of oncologic drugs in development receive regulatory approval. In addition, clinicians occasionally make therapeutic decisions based on phase II data. Therefore, clinicians, investigators, and reg...

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Detalhes bibliográficos
Publicado no:J Clin Oncol
Main Authors: Halperin, Daniel M., Lee, J. Jack, Dagohoy, Cecile Gonzales, Yao, James C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4554752/
https://ncbi.nlm.nih.gov/pubmed/26261263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2015.61.4362
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