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Rational Clinical Experiment: Assessing Prior Probability and Its Impact on the Success of Phase II Clinical Trials

PURPOSE: Despite a robust clinical trial enterprise and encouraging phase II results, the vast minority of oncologic drugs in development receive regulatory approval. In addition, clinicians occasionally make therapeutic decisions based on phase II data. Therefore, clinicians, investigators, and reg...

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Bibliographische Detailangaben
Veröffentlicht in:J Clin Oncol
Hauptverfasser: Halperin, Daniel M., Lee, J. Jack, Dagohoy, Cecile Gonzales, Yao, James C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Clinical Oncology 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4554752/
https://ncbi.nlm.nih.gov/pubmed/26261263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2015.61.4362
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