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Phase II trial design with Bayesian adaptive randomization and predictive probability
We propose a randomized phase II clinical trial design based on Bayesian adaptive randomization and predictive probability monitoring. Adaptive randomization assigns more patients to a more efficacious treatment arm by comparing the posterior probabilities of efficacy between different arms. We cont...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2012
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3832255/ https://ncbi.nlm.nih.gov/pubmed/24259753 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1467-9876.2011.01006.x |
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