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A Bayesian decision-theoretic sequential response-adaptive randomization design
We propose a class of phase II clinical trial designs with sequential stopping and adaptive treatment allocation to evaluate treatment efficacy. Our work is based on two-arm (control and experimental treatment) designs with binary endpoints. Our overall goal is to construct more efficient and ethica...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3873748/ https://ncbi.nlm.nih.gov/pubmed/23315678 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.5735 |
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