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Response-Adaptive Decision-Theoretic Trial Design: Operating Characteristics and Ethics

Adaptive randomization is used in clinical trials to increase statistical efficiency. In addition, some clinicians and researchers believe that using adaptive randomization leads necessarily to more ethical treatment of subjects in a trial. We develop Bayesian, decision-theoretic, clinical trial des...

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Detalhes bibliográficos
Main Authors: Lipsky, Ari M., Lewis, Roger J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3751997/
https://ncbi.nlm.nih.gov/pubmed/23558674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.5807
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