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A Bayesian adaptive design with biomarkers for targeted therapies

BACKGROUND: Targeted therapies are becoming increasingly important for the treatment of various diseases. Biomarkers are a critical component of a targeted therapy as they can be used to identify patients who are more likely to benefit from a treatment. Targeted therapies, however, have created majo...

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Detalhes bibliográficos
Main Authors: Eickhoff, Jens C, Kim, KyungMann, Beach, Jason, Kolesar, Jill M, Gee, Jason R
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3788617/
https://ncbi.nlm.nih.gov/pubmed/20571131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1740774510372657
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