JUN dependency in distinct early and late BRAF inhibition adaptation states of melanoma

A prominent mechanism of acquired resistance to BRAF inhibitors in BRAF(V600)-mutant melanoma is associated with the upregulation of receptor tyrosine kinases. Evidences suggested that this resistance mechanism is part of a more complex cellular adaptation process. Using an integrative strategy, we...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:Cell Discov
Glavni autori: Titz, Bjoern, Lomova, Anastasia, Le, Allison, Hugo, Willy, Kong, Xiangju, ten Hoeve, Johanna, Friedman, Michael, Shi, Hubing, Moriceau, Gatien, Song, Chunying, Hong, Aayoung, Atefi, Mohammad, Li, Richard, Komisopoulou, Evangelia, Ribas, Antoni, Lo, Roger S, Graeber, Thomas G
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5012007/
https://ncbi.nlm.nih.gov/pubmed/27648299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/celldisc.2016.28
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items