Non-genomic and Immune Evolution of Melanoma Acquiring MAPKi Resistance

Clinically acquired resistance to MAPK inhibitor (MAPKi) therapies for melanoma cannot be fully explained by genomic mechanisms and may be accompanied by co-evolution of intra-tumoral immunity. We sought to discover non-genomic mechanisms of acquired resistance and dynamic immune compositions by a c...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell
Egile Nagusiak: Hugo, Willy, Shi, Hubing, Sun, Lu, Piva, Marco, Song, ChunYing, Kong, Xiangju, Moriceau, Gatien, Hong, Aayoung, Dahlman, Kimberly B., Johnson, Douglas B., Sosman, Jeffrey A., Ribas, Antoni, Lo, Roger S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4821508/
https://ncbi.nlm.nih.gov/pubmed/26359985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.07.061
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