CRAF R391W is a melanoma driver oncogene

Approximately 75% of melanomas have known driver oncogenic mutations in BRAF, NRAS, GNA11 or GNAQ, while the mutations providing constitutive oncogenic signaling in the remaining melanomas are not known. We established a melanoma cell line from a tumor with none of the common driver mutations. This...

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Publicat a:Sci Rep
Autors principals: Atefi, Mohammad, Titz, Bjoern, Tsoi, Jennifer, Avramis, Earl, Le, Allison, Ng, Charles, Lomova, Anastasia, Lassen, Amanda, Friedman, Michael, Chmielowski, Bartosz, Ribas, Antoni, Graeber, Thomas G.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4897636/
https://ncbi.nlm.nih.gov/pubmed/27273450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27454
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