Effects of MAPK and PI3K Pathways on PD-L1 Expression in Melanoma

PURPOSE: PD-L1 is the main ligand for the immune inhibitory receptor PD-1. This ligand is frequently expressed by melanoma cells. In this study we investigated whether PD-L1 expression is controlled by melanoma driver mutations and modified by oncogenic signaling inhibition. EXPERIMENTAL DESIGN: Exp...

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Detalhes bibliográficos
Main Authors: Atefi, Mohammad, Avramis, Earl, Lassen, Amanda, Wong, Deborah, Robert, Lidia, Foulad, David, Cerniglia, Michael, Titz, Bjoern, Chodon, Thinle, Graeber, Thomas G., Comin-Anduix, Begonya, Ribas, Antoni
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4079734/
https://ncbi.nlm.nih.gov/pubmed/24812408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-2797
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