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ST-11: a new brain-penetrant microtubule-destabilizing agent with therapeutic potential for glioblastoma multiforme

Glioblastoma multiforme (GBM) is a devastating and intractable type of cancer. Current antineoplastic drugs do not improve the median survival of patients diagnosed with GBM beyond 14–15 months in part because the blood-brain barrier is generally impermeable to many therapeutic agents. Drugs that ta...

詳細記述

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書誌詳細
出版年:Mol Cancer Ther
主要な著者: Cherry, Allison E., Haas, Brian R., Naydenov, Alipi V., Fung, Susan, Xu, Cong, Swinney, Katie, Wagenbach, Michael, Freeling, Jennifer, Canton, David A., Coy, Jonathan, Horne, Eric A., Rickman, Barry, Vicente, Juan Jesus, Scott, John D., Ho, Rodney J. Y., Liggitt, Denny, Wordeman, Linda, Stella, Nephi
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5010991/
https://ncbi.nlm.nih.gov/pubmed/27325686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-15-0800
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