DDIS-14. MODIFIED CARBAZOLES DESTABILIZE MICROTUBULES AND KILL GLIOBLASTOMA MULTIFORM CELLS

Small molecules that target microtubules (MTs) represent promising therapeutics to treat certain types of cancer, including glioblastoma multiform (GBM). We synthesized modified carbazoles and evaluated their antitumor activity in GBM cells in culture. Modified carbazoles with an ethyl moiety linked...

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Vydáno v:Neuro Oncol
Hlavní autoři: Stella, Nephi, Diaz, Philippe, Horne, Eric, Xu, Cong, Hamel, Ernest, Wagenbach, Mike, Petrov, Ravil, Hass, Brian, Parvinder, Hothi, Wordeman, Linda, Gussio, Rick
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216603/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.293
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