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Selection of RNA aptamers against botulinum neurotoxin type A light chain through a non-radioactive approach
Botulinum neurotoxin (BoNT), a category A agent, is the most toxic molecule known to mankind. The endopeptidase activity of light chain domain of BoNT is the cause for the inhibition of the neurotransmitter release and the flaccid paralysis that leads to lethality in botulism. Currently, antidotes a...
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| Pubblicato in: | Appl Biochem Biotechnol |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5010959/ https://ncbi.nlm.nih.gov/pubmed/27085355 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12010-016-2081-0 |
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