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In Vitro selection of RNA aptamers that inhibit the activity of type A botulinum neurotoxin
The category A agent, botulinum neurotoxin (BoNT), is the most toxic molecule known to mankind. The endopeptidase activity of light chain domain of BoNT is the cause for the inhibition of the neurotransmitter release and the flaccid paralysis that leads to lethality in botulism. Currently, antidotes...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2891020/ https://ncbi.nlm.nih.gov/pubmed/20452328 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2010.05.006 |
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