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Role of Neurotoxin Associated Proteins in the Low pH Induced Structural Changes in the Botulinum Neurotoxin Complex

BoNT (Botulinum Neurotoxin) produced by the bacterium Clostridium botulinum as a complex with NAPs causes botulism. It has been known that the NAPs protect the toxin from both extremes of pHs and proteases of the GI tract. In an attempt to emulate the physiological conditions encountered by the toxi...

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Detalhes bibliográficos
Publicado no:Protein J
Main Authors: Chellappan, Gowri, Kumar, Raj, Cai, Shuowei, Singh, Bal Ram
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4308291/
https://ncbi.nlm.nih.gov/pubmed/25408485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10930-014-9588-4
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