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Role of Neurotoxin Associated Proteins in the Low pH Induced Structural Changes in the Botulinum Neurotoxin Complex
BoNT (Botulinum Neurotoxin) produced by the bacterium Clostridium botulinum as a complex with NAPs causes botulism. It has been known that the NAPs protect the toxin from both extremes of pHs and proteases of the GI tract. In an attempt to emulate the physiological conditions encountered by the toxi...
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| Veröffentlicht in: | Protein J |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4308291/ https://ncbi.nlm.nih.gov/pubmed/25408485 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10930-014-9588-4 |
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