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Selection of RNA aptamers against botulinum neurotoxin type A light chain through a non-radioactive approach
Botulinum neurotoxin (BoNT), a category A agent, is the most toxic molecule known to mankind. The endopeptidase activity of light chain domain of BoNT is the cause for the inhibition of the neurotransmitter release and the flaccid paralysis that leads to lethality in botulism. Currently, antidotes a...
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| Udgivet i: | Appl Biochem Biotechnol |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5010959/ https://ncbi.nlm.nih.gov/pubmed/27085355 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12010-016-2081-0 |
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