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Dual and specific inhibition of NAMPT and PAK4 by KPT-9274 decreases kidney cancer growth

Kidney cancer (or renal cell carcinoma, RCC) is the sixth most common malignancy in the US and one of the relatively few whose incidence is increasing. Due to the near universal resistance which occurs with the use of current treatment regimens, reprogrammed metabolic pathways are being investigated...

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Detalhes bibliográficos
Publicado no:Mol Cancer Ther
Main Authors: Aboud, Omran Abu, Chen, Ching-Hsien, Senapedis, William, Baloglu, Erkan, Argueta, Christian, Weiss, Robert H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5010932/
https://ncbi.nlm.nih.gov/pubmed/27390344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-16-0197
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