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An analytical workflow for accurate variant discovery in highly divergent regions
BACKGROUND: Current variant discovery methods often start with the mapping of short reads to a reference genome; yet, their performance deteriorates in genomic regions where the reads are highly divergent from the reference sequence. This is particularly problematic for the human leukocyte antigen (...
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| Publicat a: | BMC Genomics |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5010666/ https://ncbi.nlm.nih.gov/pubmed/27590916 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-3045-z |
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