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Comparative analysis of de novo assemblers for variation discovery in personal genomes
Current variant discovery approaches often rely on an initial read mapping to the reference sequence. Their effectiveness is limited by the presence of gaps, potential misassemblies, regions of duplicates with a high-sequence similarity and regions of high-sequence divergence in the reference. Also,...
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| Publicado no: | Brief Bioinform |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6169673/ https://ncbi.nlm.nih.gov/pubmed/28407084 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bib/bbx037 |
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